Catechol-O-methyltransferase val158met genotype determines effect of reboxetine on emotional memory in healthy male volunteers
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چکیده
منابع مشابه
Catechol-O-methyltransferase val158met genotype determines effect of reboxetine on emotional memory in healthy male volunteers.
BACKGROUND Catechol-O-methyltransferase (COMT) metabolizes catecholamines in the prefrontal cortex (PFC). A common polymorphism in the COMT gene (COMT val158met) has pleiotropic effects on cognitive and emotional processing. The met allele has been associated with enhanced cognitive processing but impaired emotional processing relative to the val allele. METHODS We genotyped healthy, white me...
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ژورنال
عنوان ژورنال: Journal of Psychiatry & Neuroscience
سال: 2014
ISSN: 1180-4882
DOI: 10.1503/jpn.130131